Dr Dave Moskowitz's special guest is Ram Nadathur, a geneticist and biotechnology expert who works for one of the leading DNA sequencing companies. He is an expert in precision medicine and genetics, and has a gift for explaining things. Our quest is to make knowledge accessible.
Here are some of the points we could touch on:
Finding disease-variant associations
Who pays?Where do the patients come from?Correction for ethnicityRe-purposing drugs
Who does the clinical research?Spreading the word to primary care providers
UpToDate? Doximity?Note: already existing protocols are being ignored: CKD, COPD, sickle cell, COVIDNew drugs: Prophase Labs?Diseases to solve:
Cancer: prediction, treatment (metastatic disease: differentiation therapy)Dementia: prediction & treatmentModifier genes for single gene disorders like CF, Huntington's, etc.