San Francisco 49ers vs. Philadelphia Eagles Pick Prediction 9/19/2021 by Tony T.
49ers at Eagles—Free pick is Philadelphia Eagles +3. Eagles played great for all four quarters in their win against the Falcons on the road. 49ers likely played one of the worst teams in the league in Detroit and gave up a lot of fourth quarter points and yardage. San Francisco defensively didn't look conditioned to play a full four quarters. Jalen Hurts with a normal training camp now in his second year showed great improvement completing 27 of 35 for 264 yards and three touchdowns. Eagles run game did produce 173 yards in the opener for 5.6 yards per pass attempt. 49ers bad injury luck from last year continued at the start of this season as lead running back Raheem Mostert and cornerback Jason Verrett are out. San Francisco is thin at corner. Play Philadelphia +3.