Denver Broncos vs. Indianapolis Colts NFL Pick Prediction 9/14/2025 by Tony T.
Broncos at Colts Injuries
Denver has a linebacker out. Indianapolis has a defensive end questionable and a corner out. Denver has a slight injury advantage based on the Chao ratings by +2.
Recent Box Score Key Stats
Broncos at Colts 4PM ET—Denver is 1-0 with their 20-12 home victory against Tennessee. The Broncos rushed for 151 yards averaging five yards a carry. Passing game sputtered mightily. Their defense smashed the Titans offense by allowing only 133 yards. Bo Nix hit 25 of 40 for 176 yards with a touchdown and two picks. Indianapolis sits at 1-0 after their 33-8 home victory against Miami. Indianapolis rushed for 156 yards and were efficient passing. They held the Dolphins to 221 yards with 4.3 yards per pass attempt. Daniel Jones hit 22 of 29 for 272 yards and a touchdown. He rushed for 26 yards and two touchdowns.