Pittsburgh Steelers vs. New England Patriots NFL Pick Prediction 9/21/2025 by Tony T.
Steelers vs. Patriots Injuries
Pittsburgh has a linebacker, corner and safety out with a defensive end questionable. New England fullback and a corner are questionable. New England has a clear injury advantage based on the Chao ratings by +4.70.
Recent Box Score Key Stats
Steelers at Patriots 1PM ET—Pittsburgh is 1-1 after their 31-17 home defeat to Seattle. The Steelers rushed for only 72 yards and were inefficient in the passing game. They held the Seahawks to 4 yards a carry but struggled defending the pass. Aaron Rodgers hit 18 of 33 for 203 yards with a touchdown and two picks. New England is 1-1 with their 33-27 road win at Miami. The Patriots rushed for 4.2 yards a carry and effective in the passing game. They limited the Dolphins to 61 yards rushing but 297 yards passing for 9.3 yards a pass attempt. Drake Maye hit 19 of 23 for 230 yards with two touchdowns. He rushed for 31 yards and a score.