9/27/25 Duke vs Syracuse NCAAF Picks and Predictions Week 5


9/27/25 Duke vs Syracuse NCAAF Picks and Predictions Week 5


Duke vs. Syracuse College Football Pick Prediction 9/27/2025 by Tony T.

Recent Box Score Key Stats

Duke at Syracuse 12PM ET—Duke is 2-2 following their 45-33 home victory against NC State. The Blue Devils rushed for 149 yards for 4.2 yards a carry and were effective throwing the football. But defensively they allowed 171 yards rushing to the Wolf Pack for 4.9 yards a carry with 364 yards passing for 9.3 yards per pass attempt.