9/27/25 USC vs Illinois NCAAF Picks and Predictions Week 5


9/27/25 USC vs Illinois NCAAF Picks and Predictions Week 5


USC vs. Illinois College Football Pick Prediction 9/27/2025 by Tony T.

Recent Box Score Key Stats

USC at Illinois 12PM ET—USC is 4-0 following their 45-31 home victory against Michigan St. The Trojans rushed for 289 yards for 7.2 yards a carry and effective through the air. Defensively they limited the Spartans ground attack and allowed 225 yards passing for 9.8 yards per pass attempt.