LA Rams vs. San Francisco 49ers NFL Pick Prediction 11/9/2025 by Tony T.
Rams vs. 49ers Injuries
LA receiver Washington is questionable. San Francisco receiver Pearsall is out with quarterback Purdy questionable to serve as a backup. On defense their tackles and two linebackers are questionable. LA has a massive injury advantage based on the Chao ratings. The San Francisco defense has the lowest rating at 61.
Recent Box Score Key Stats
Rams at 49ers 4:25PM ET—LA improved to 6-2 following their 34-10 home victory against New Orleans. The Rams gained 438 yards with good work in the run and pass. On defense they held the Saints to 57 rushing yards with 167 yards passing for 6.7 yards per pass attempt. Matthew Stafford completed 24 of 32 for 281 yards with four touchdowns. San Francisco is 6-3 after their 34-24 road win at NY Giants. The 49ers had movement in the passing game and rushed for 159 yards for 4.1 yards per pass attempt. On defense they limited the Giants through the air and allowed 117 yards rushing for 5.6 yards a carry. Mac Jones hit 19 of 24 for 235 yards with two touchdowns. Jones will get the start.