Toledo vs. Louisville College Football Pick Prediction 12/23/2025 by Tony T.
Toledo vs. Louisville Team Profiles
Toledo vs. Louisville 2PM ET—Toledo is 8-4 following their 21-3 road victory against Central Michigan. Rockets were balanced in victory with 411 yards and did a good job in defending the run. Louisville is 8-4 after a 41-0 home victory against Kentucky. Cardinal's defense held the Wildcats to 140 yards while rushing offensively for 258 yards.