San Francisco 49ers vs. Philadelphia Eagles NFL Pick Prediction 1/11/2026 by Tony T.
49ers vs. Eagles Injuries
San Francisco receiver Pearsall and left tackle Williams are questionable. On defense a linebacker is out with a linebacker and corner questionable. Philadelphia fullback is out with right tackle questionable. Philadelphia has a significant injury advantage based on the Chao ratings of +14.50. Eagles' offense has the healthiest rating at 90.5 with the 49ers defense the lowest health rating at 65.6.
Recent Box Score Key Stats
49ers at Eagles 4:30PM ET—San Francisco is 12-5 following their 13-3 home defeat against Seattle. It was a poor offensive showing by the 49ers that gained 173 yards and cost them the number one seed and division title. They surrendered 180 rushing yards in defense. Philadelphia is 11-6 following their 24-17 home defeat against Washington. Eagles had clinched the NFC East and had no shot for a one seed so they rested their starters.